Platelet rich stroma treatment knee arthritis India

Platelet-rich stroma (PRS) is a non-surgical treatment for knee osteoarthritis that has gained popularity in recent years. It is a combination of platelet-rich plasma (PRP) and stromal vascular fraction (SVF) that includes stromal cells in their matrix with stimulating factors and plays an important role in reducing articular inflammation and signaling cartilage repair in osteoarthritis ¹. PRS contains SVF obtained from fat, which is a better source of multipotential signaling cells than bone marrow. Fat is harvested by mini liposuction from the thigh, buttocks, or abdominal fat through tiny incisions. The incisions heal naturally without sutures. PRP is prepared from venous blood. It concentrates platelets several fold times. Platelets contain growth factors that assist in tissue repair. It is injected into the knee under ultrasound guidance. Ultrasound-guided knee injections are more accurate than blind injections ¹.

PRS therapy is an effective treatment option for knee osteoarthritis in several studies. A study by Hieronymus Stevens found that PRS therapy can provide significant pain relief and improved function in patients with knee osteoarthritis. In this study, patients received a single injection of PRS into their affected knee joint ². Another study by Dr. A.K. Venkatachalam found that PRS relieves the pain of osteoarthritis immediately and its effect can last for a few years. Over a period of time, limited cartilage repair is seen ¹.

The procedure is performed under local anesthesia and is injected under ultrasound guidance. Keyhole surgery (arthroscopy) or spinal anesthesia is not involved in the procedure. No spinal anesthesia is required. Keyhole surgery is not used. Both knees can be done in one sitting. The patient walks into the operating room and walks out after the procedure. They experience immediate pain relief ¹.

The preparation, processing, and application techniques are vital to achieving satisfactory results. Many studies have examined outcomes after PRP injection, with encouraging results. The results of combining PRP and SVF has proved to be good in my practice. I have a standard practice of isolating high concentration PRP and getting properly concentrated and double dose of SVF from only 30 ml of adipose tissue.

In conclusion, PRS is a revolutionary procedure to treat osteoarthritis of the knee. It is a non-surgical treatment that relieves pain immediately and its effect can last for a few years. Over a while, limited cartilage repair is seen. PRS therapy is an effective treatment option for knee osteoarthritis in several studies. The procedure is performed under local anesthesia and is injected under ultrasound guidance. Keyhole surgery (arthroscopy) or spinal anesthesia is not involved in the procedure. No spinal anesthesia is required. Keyhole surgery is not used. Both knees can be done in one sitting. The patient walks into the operating room and walks out after the procedure. They experience immediate pain relief. However, the preparation, processing, and application techniques are vital to achieving satisfactory results ¹³.